PACAP induces light aversion in mice by an inheritable mechanism independent of CGRP

A Kuburas, BN Mason, B Hing, AS Wattiez… - Journal of …, 2021 - Soc Neuroscience
mice. Importantly, an anti-PACAP monoclonal antibody could block PACAP-induced light
aversion but not CGRP-induced light aversion. … involved in pain modulation. These include the …

Vascular actions of peripheral CGRP in migraine-like photophobia in mice

BN Mason, AS Wattiez, LK Balcziak, A Kuburas… - …, 2020 - journals.sagepub.com
… or just a correlative role in CGRP-induced light aversion, we used … Phenylephrine is a
potent and selective agonist of α-… only examined aversion to bright light in wild-type mice and …

[HTML][HTML] CGRP induces migraine-like symptoms in mice during both the active and inactive phases

AS Wattiez, OJ Gaul, A Kuburas, E Zorrilla… - The journal of headache …, 2021 - Springer
… the validity of CGRP-induced behavioral changes in mice by … of migraine-like light aversion
and squint response in mice by CGRP is not … Dural administration of the TRPA1 agonist allyl …

[HTML][HTML] CGRP administration into the cerebellum evokes light aversion, tactile hypersensitivity, and nociceptive squint in mice

M Wang, TL Duong, BJ Rea, JS Waite… - Frontiers in Pain …, 2022 - frontiersin.org
… of CGRP induced similar light-aversive behaviors in wild-type … Fluorescein-15-CGRP is a
full CGRP receptor agonist but has less … that are modulated by CGRP in the MN are unknown. …

Investigating migraine-like behavior using light aversion in mice

M Wang, BN Mason, LP Sowers, A Kuburas… - JoVE (Journal of …, 2021 - jove.com
… with light aversion using transgenic nestin/hRAMP1 mice in … exhibit photophobia 11 , light
aversion is considered to be an … CGRP-induced light aversion in both CD1 and C57BL/6J …

[HTML][HTML] Stimulation of CGRP-expressing neurons in the medial cerebellar nucleus induces light and touch sensitivity in mice

M Wang, WC Castonguay, TL Duong, MW Huebner… - Neurobiology of …, 2022 - Elsevier
… strategy using Calca Cre/+ mice to drive Cre-dependent … migraine symptoms, including light
aversion, cutaneous allodynia, … decreased the time spent in the light, which was coupled to …

Human RAMP1 overexpressing mice are resistant to migraine therapies for motion sensitivity: a mouse model of vestibular migraine

SM Rahman, L Guo, C Minarovich, L Moon, A Guo… - bioRxiv, 2023 - biorxiv.org
Modulation of CGRP-induced light 413 aversion in wild-type mice by a 5-HT(1B/D) agonist.
J Neurosci 2012; 32: 15439-15449. 414 DOI: 10.1523/JNEUROSCI.3265-12.2012. 415 17. …

CGRP physiology, pharmacology, and therapeutic targets: migraine and beyond

AF Russo, DL Hay - Physiological reviews, 2023 - journals.physiology.org
… CGRP this modulation is not limited to the nervous system. … reporter genes in cell cultures
and transgenic mice. A 1.7-kb 5… Serotonin receptor (5-HT 1B/D/F ) agonists that include triptan …

Calcitonin gene-related peptide (CGRP): role in migraine pathophysiology and therapeutic targeting

AS Wattiez, LP Sowers, AF Russo - Expert opinion on therapeutic …, 2020 - Taylor & Francis
… The modulation of neural activity in the meninges could trigger … demonstrated that
CGRP-induced pain was light independent… and peripheral CGRP injection in wild-type mice, and it …

CGRP Administration into the Cerebellum Evokes Migraine-like Behaviors Predominately in Female Mice

M Wang, TL Duong, BJ Rea, JS Waite, MW Huebner… - bioRxiv, 2022 - biorxiv.org
… of CGRP induced similar light-aversive behaviors in wild-type … Fluorescein-15-CGRP is a
full CGRP receptor agonist but has less … that are modulated by CGRP in the MN are unknown. …